Spdef - SAM pointed domain containing ets transcription factor Gene

Rattus norvegicus

Gene ID: 689210 | Gene type: protein coding

About Spdef

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Predicted to be involved in cell differentiation; positive regulation of apoptotic process; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including columnar/cuboidal epithelial cell differentiation; positive regulation of cell fate commitment; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human SPDEF (SAM pointed domain containing ETS transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Spdef Products(1)

mRNA	Protein	Name
NM_001109530.2	NP_001103000.1	SAM pointed domain-containing Ets transcription factor

Protein Preferred Names

Protein Names

SAM pointed domain-containing Ets transcription factor

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B0603	Fluticasone	Agonist	98.70%	Yes

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13652	SPDEF Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS17775	Spdef Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24242	Spdef Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Spdef	NCBI	NCBI:25803

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