2. Gene
  3. Nexn - nexilin Gene

Nexn - nexilin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as NELIN; 1110046H09Rik

Gene ID: 68810 | Gene type: protein coding

About Nexn

Summary

Predicted to enable actin filament binding activity and cell-cell adhesion mediator activity. Predicted to be a structural constituent of muscle. Acts upstream of or within response to bacterium. Predicted to be located in Z disc; actin cytoskeleton; and focal adhesion. Predicted to be active in axon and plasma membrane. Is expressed in diaphragm; gut; head mesenchyme; heart; and vertebral axis musculature. Used to study dilated cardiomyopathy 1CC and hypertrophic cardiomyopathy 20. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1CC and hypertrophic cardiomyopathy 20. Orthologous to human NEXN (nexilin F-actin binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Nexn Products(2)

mRNA Protein Name
NM_001357206.2 NP_001344135.1 nexilin isoform 1
NM_199465.4 NP_955759.2 nexilin isoform 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nexilin

F-actin-binding protein

nF actin binding protein

nexilin alpha

nexilin beta

nexilin gamma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09232 NEXN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22253 Nexn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28775 Nexn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nexn NCBI NCBI:91624