2. Gene
  3. Mnx1 - motor neuron and pancreas homeobox 1 Gene

Mnx1 - motor neuron and pancreas homeobox 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hlxb9

Gene ID: 682076 | Gene type: protein coding

About Mnx1

Summary

Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in endocrine pancreas development; neuron projection morphogenesis; and spinal cord motor neuron cell fate specification. Predicted to act upstream of or within several processes, including diaphragm development; nervous system development; and pancreas development. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Currarino syndrome. Orthologous to human MNX1 (motor neuron and pancreas homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Mnx1 Products(1)

mRNA Protein Name
NM_001271274.1 NP_001258203.1 motor neuron and pancreas homeobox protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
18539116 RGD
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
18539116 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18539116 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

motor neuron and pancreas homeobox protein 1

homeobox gene HB9

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08571 MNX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20296 Mnx1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26804 Mnx1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mnx1 NCBI NCBI:3110