2. Gene
  3. Mbd4 - methyl-CpG binding domain 4 DNA glycosylase Gene

Mbd4 - methyl-CpG binding domain 4 DNA glycosylase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 680915 | Gene type: protein coding

About Mbd4

Summary

Predicted to enable DNA binding activity and pyrimidine-specific mismatch base pair DNA N-glycosylase activity. Involved in response to estradiol. Predicted to be located in chromatin; cytoplasm; and nuclear speck. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in colorectal carcinoma; esophagus squamous cell carcinoma; lung cancer; and rheumatoid arthritis. Orthologous to human MBD4 (methyl-CpG binding domain 4, DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Mbd4 Products(1)

mRNA Protein Name
XM_001059437.7 XP_001059437.3 methyl-CpG-binding domain protein 4
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to estradiol IEP
IEP: Inferred from expression pattern
22109888 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methyl-CpG-binding domain protein 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08184 MBD4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19616 Mbd4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26111 Mbd4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mbd4 NCBI NCBI:8930