2. Gene
  3. Nsd2 - nuclear receptor binding SET domain protein 2 Gene

Nsd2 - nuclear receptor binding SET domain protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Whsc1; RGD1565590

Gene ID: 680537 | Gene type: protein coding

About Nsd2

Summary

Predicted to enable chromatin binding activity; Histone Methyltransferase activity (H3-K36 specific); and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including cardiac septum morphogenesis; histone lysine methylation; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in chromatin and nucleus. Human ortholog(s) of this gene implicated in Wolf-Hirschhorn syndrome. Orthologous to human NSD2 (nuclear receptor binding SET domain protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Nsd2 Products(1)

mRNA Protein Name
NM_001191552.2 NP_001178481.2 histone-lysine N-methyltransferase NSD2
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase NSD2

Wolf-Hirschhorn syndrome candidate 1

probable histone-lysine N-methyltransferase NSD2

Related Agents

Pre-clinical Phase
Bioactive Molecules (33)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100034 NSC 663284 Inhibitor 99.29% Unkown
HY-114208A BI-9321 trihydrochloride Antagonist 99.83% Unkown
HY-157251 UNC8153 TFA Degrader 99.92% Unkown
HY-161574 LLC0424 Inhibitor 98.42% Unkown
HY-151101 MS159 98.28% Unkown
HY-138283 MR837 Inhibitor 99.82% Unkown
HY-145103 UNC6934 Chemical 99.15% Unkown
HY-114340 LEM-14 Inhibitor 98.06% Unkown
HY-154812 Gintemetostat Inhibitor 99.81% Unkown
HY-15647 BRD9539 Inhibitor 99.74% Unkown
HY-162308 NSD-IN-3 ≥98.0% Unkown
HY-171119 NSD2-PWWP1-IN-1 Inhibitor 98.72% Unkown
HY-161575 NSD2 ligand 1 99.76% Unkown
HY-171121 NSD2-PWWP1-IN-3 Inhibitor 99.63% Unkown
HY-168035 W4275 Inhibitor 98.93% Unkown
HY-171120 NSD2-PWWP1-IN-2 Inhibitor 99.64% Unkown
HY-125244 LEM-14-1189 Inhibitor 99.57% Unkown
HY-157251A UNC8153 Degrader 99.13% Unkown
HY-147914 NSD2-IN-1 Inducer 98.72% Unkown
HY-161796A UNC8732 TFA Inhibitor / Unkown
HY-114208 BI-9321 Antagonist / Unkown
HY-124699 MMSET-IN-1 Inhibitor / Unkown
HY-155817 UNC7096 Chemical / Unkown
HY-155818 NSD2-IN-4 Inhibitor / Unkown
HY-161576 Thalidomide-Pip-N-boc / Unkown
HY-161670 NSD2-PWWP1 ligand 1 Inhibitor / Unkown
HY-161796 UNC8732 / Unkown
HY-170674 ND-L11B free base Degrader / Unkown
HY-170674A ND-L11B TFA Degrader / Unkown
HY-172614 RK-0080552 Inhibitor / Unkown
HY-RS09588 NSD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16731 Nsd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23167 Nsd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nsd2 NCBI NCBI:7468