2. Gene
  3. Pam16 - presequence translocase associated motor 16 Gene

Pam16 - presequence translocase associated motor 16 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Magmas

Gene ID: 679907 | Gene type: protein coding

About Pam16

Summary

Involved in negative regulation of apoptotic DNA fragmentation and negative regulation of release of cytochrome c from mitochondria. Predicted to be located in mitochondrial matrix. Predicted to be extrinsic component of mitochondrial inner membrane. Predicted to be part of PAM complex, Tim23 associated import motor. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia Megarbane-Dagher-Melike type. Orthologous to human PAM16 (presequence translocase associated motor 16). [provided by Alliance of Genome Resources, Apr 2022]

Pam16 Products(1)

mRNA Protein Name
NM_001100136.2 NP_001093606.2 mitochondrial import inner membrane translocase subunit TIM16
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of apoptotic DNA fragmentation IDA
IDA: Inferred from direct assay
24069394 RGD
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
24069394 RGD
involved in negative regulation of release of cytochrome c from mitochondria IDA
IDA: Inferred from direct assay
24069394 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial import inner membrane translocase subunit TIM16

mitochondria-associated granulocyte macrophage CSF signaling molecule

mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction

presequence translocase associated motor 16 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10012 PAM16 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19468 Pam16 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25961 Pam16 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pam16 NCBI NCBI:51025