2. Gene
  3. Tctn2 - tectonic family member 2 Gene

Tctn2 - tectonic family member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tect2; 4432405B04Rik

Gene ID: 67978 | Gene type: protein coding

About Tctn2

Summary

Involved in cilium assembly; protein localization to ciliary transition zone; and smoothened signaling pathway. Located in ciliary transition zone. Part of MKS complex. Is expressed in several structures, including central nervous system; retina; and turbinate bone primordium. Human ortholog(s) of this gene implicated in Joubert syndrome 24 and Meckel syndrome 8. Orthologous to human TCTN2 (tectonic family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Tctn2 Products(1)

mRNA Protein Name
NM_026486.3 NP_080762.1 tectonic-2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
22179047 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
21565611 MGI
involved in protein localization to ciliary transition zone IMP
IMP: Inferred from mutant phenotype
26982032 MGI
involved in smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
21565611 MGI
Cellular Component GO Annotation Evidence Reference Source
part of MKS complex IDA
IDA: Inferred from direct assay
21725307 MGI
located in ciliary transition zone IDA
IDA: Inferred from direct assay
29487109 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tectonic-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14327 TCTN2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22850 Tctn2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tctn2 NCBI NCBI:79867