2. Gene
  3. Wdr48 - WD repeat domain 48 Gene

Wdr48 - WD repeat domain 48 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Uaf1; mKIAA1449; 8430408H12Rik

Gene ID: 67561 | Gene type: protein coding

About Wdr48

Summary

Predicted to enable double-stranded DNA binding activity; single-stranded DNA binding activity; and ubiquitin binding activity. Acts upstream of or within several processes, including animal organ development; double-strand break repair via homologous recombination; and regulation of protein monoubiquitination. Predicted to be located in nucleus. Is expressed in femur. Orthologous to human WDR48 (WD repeat domain 48). [provided by Alliance of Genome Resources, Apr 2022]

Wdr48 Products(1)

mRNA Protein Name
NM_026236.3 NP_080512.1 WD repeat-containing protein 48
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within DNA damage response IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within double-strand break repair via homologous recombination IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within embryonic organ development IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within homeostasis of number of cells IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within male gonad development IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within regulation of protein monoubiquitination IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within seminiferous tubule development IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within single fertilization IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within skeletal system morphogenesis IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within skin development IMP
IMP: Inferred from mutant phenotype
24001775 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
24001775 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

WD repeat-containing protein 48

USP1-associated factor 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15784 WDR48 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22921 Wdr48 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wdr48 NCBI NCBI:57599