2. Gene
  3. Mastl - microtubule associated serine/threonine kinase-like Gene

Mastl - microtubule associated serine/threonine kinase-like Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as GW; GWL; THC2; MAST-L; 2700091H24Rik

Gene ID: 67121 | Gene type: protein coding

About Mastl

Summary

Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within female meiosis II and positive regulation of ubiquitin protein Ligase activity. Predicted to be located in centrosome; cleavage furrow; and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including early conceptus; otic capsule; secondary oocyte; thymus primordium; and tooth. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human MASTL (microtubule associated serine/threonine kinase like). [provided by Alliance of Genome Resources, Apr 2022]

Mastl Products(2)

mRNA Protein Name
NM_025979.4 NP_080255.3 serine/threonine-protein kinase greatwall
NM_025979.4 NP_080255.3 serine/threonine-protein kinase greatwall
Protein Preferred Names Protein Names

serine/threonine-protein kinase greatwall

microtubule-associated serine/threonine-protein kinase-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-137552 MKI-1 Inhibitor 98.13% Unkown
HY-156716 MASTL-IN-2 Inhibitor 98.49% Unkown
HY-156715 MASTL-IN-1 Inhibitor 99.54% Unkown
HY-W231513 MASTL/Aurora A-IN-1 Inhibitor / Unkown
HY-162731 MASTL-IN-3 Inhibitor / Unkown
HY-162732 MASTL-IN-4 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mastl NCBI NCBI:84930