2. Gene
  3. Fgf22 - fibroblast growth factor 22 Gene

Fgf22 - fibroblast growth factor 22 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Fgf5d; FGF-22; 2210414E06Rik

Gene ID: 67112 | Gene type: protein coding

About Fgf22

Summary

Predicted to enable Fibroblast Growth Factor receptor binding activity and growth factor activity. Predicted to be involved in several processes, including Fibroblast Growth Factor receptor signaling pathway; positive regulation of cell population proliferation; and positive regulation of macromolecule metabolic process. Located in Golgi apparatus; cell surface; and nucleolus. Is expressed in brain; early conceptus; gonad; and spinal cord. Orthologous to human FGF22 (Fibroblast Growth Factor 22). [provided by Alliance of Genome Resources, Apr 2022]

Fgf22 Products(2)

mRNA Protein Name
NM_001368662.1 NP_001355591.1 fibroblast growth factor 22 isoform 2 precursor
NM_023304.2 NP_075793.1 fibroblast growth factor 22 isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15806171 MGI
Biological Process GO Annotation Evidence Reference Source
involved in regulation of synapse maturation IDA
IDA: Inferred from direct assay
20505669 MGI
involved in regulation of synapse maturation IMP
IMP: Inferred from mutant phenotype
20505669 MGI
involved in trans-synaptic signaling IDA
IDA: Inferred from direct assay
27627962 MGI
involved in trans-synaptic signaling IMP
IMP: Inferred from mutant phenotype
27627962 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
20505669 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
20505669 MGI
located in Golgi apparatus IDA
IDA: Inferred from direct assay
12837279 MGI
located in cell surface IDA
IDA: Inferred from direct assay
12837279 MGI
NOT located in extracellular region IDA
IDA: Inferred from direct assay
12837279 MGI
is active in extrinsic component of postsynaptic density membrane IDA
IDA: Inferred from direct assay
27627962 MGI
is active in extrinsic component of postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
27627962 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
20505669 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
20505669 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
12837279 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
20505669 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
20505669 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 22

fibroblast growth factor 5d

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148432 FGF22-IN-1 Inhibitor 98.07% Unkown
HY-RS04899 FGF22 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19434 Fgf22 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25925 Fgf22 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf22 NCBI NCBI:27006