2. Gene
  3. Paics - phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase Gene

Paics - phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as AIRC; PAIS; ADE2H1; 2610511I09Rik

Gene ID: 67054 | Gene type: protein coding

About Paics

Summary

Predicted to enable identical protein binding activity; phosphoribosylaminoimidazole carboxylase activity; and phosphoribosylaminoimidazolesuccinocarboxamide synthase activity. Predicted to be involved in purine ribonucleoside monophosphate biosynthetic process. Predicted to act upstream of or within purine nucleotide biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase). [provided by Alliance of Genome Resources, Apr 2022]

Paics Products(5)

mRNA Protein Name
NM_001356971.1 NP_001343900.1 bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform a
NM_001356972.1 NP_001343901.1 bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform a
NM_001356973.1 NP_001343902.1 bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform a
NM_001356974.1 NP_001343903.1 bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform b
NM_025939.3 NP_080215.1 bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform a
Protein Preferred Names Protein Names

bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

multifunctional protein ADE2

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148218 N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine / Unkown
HY-RS09980 PAICS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21010 Paics Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27527 Paics Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Paics NCBI NCBI:10606