2. Gene
  3. Trim35 - tripartite motif-containing 35 Gene

Trim35 - tripartite motif-containing 35 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as NC8; HLS5; Mair; mKIAA1098; 0710005M05Rik; A430106H13Rik

Gene ID: 66854 | Gene type: protein coding

About Trim35

Summary

Predicted to enable ubiquitin protein Ligase activity. Acts upstream of or within negative regulation of cell population proliferation and positive regulation of apoptotic process. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; lung; and sensory organ. Orthologous to human TRIM35 (tripartite motif containing 35). [provided by Alliance of Genome Resources, Apr 2022]

Trim35 Products(1)

mRNA Protein Name
NM_029979.3 NP_084255.2 E3 ubiquitin-protein ligase TRIM35
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25907537 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of myeloid cell apoptotic process IDA
IDA: Inferred from direct assay
12692137 MGI
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
14662771 MGI
acts upstream of or within positive regulation of myeloid cell apoptotic process IDA
IDA: Inferred from direct assay
12692137 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12692137 MGI
located in nucleus IDA
IDA: Inferred from direct assay
14662771 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM35

hemopoietic lineage switch protein 5

macrophage-derived apoptosis-inducing RBCC protein

protein Nc8

tripartite motif-containing protein 35

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15039 TRIM35 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21209 Trim35 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim35 NCBI NCBI:23087