Ube2w - ubiquitin-conjugating enzyme E2W (putative) Gene

Mus musculus

Also known as 6130401J04Rik

Gene ID: 66799 | Gene type: protein coding

About Ube2w

Summary

Enables ubiquitin conjugating enzyme activity and ubiquitin protein Ligase binding activity. Involved in cellular response to misfolded protein; protein monoubiquitination; and proteolysis involved in cellular protein catabolic process. Located in nucleus. Orthologous to human UBE2W (ubiquitin conjugating enzyme E2 W). [provided by Alliance of Genome Resources, Apr 2022]

Ube2w Products(3)

mRNA	Protein	Name
NM_001271016.2	NP_001257945.2	ubiquitin-conjugating enzyme E2 W isoform 2
NM_001271017.2	NP_001257946.2	ubiquitin-conjugating enzyme E2 W isoform 3
NM_025773.4	NP_080049.3	ubiquitin-conjugating enzyme E2 W isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21229326	MGI
enables ubiquitin conjugating enzyme activity	IDA IDA: Inferred from direct assay	21229326	MGI
enables ubiquitin protein ligase binding	IPI IPI: Inferred from physical interaction	21855799	MGI
enables ubiquitin-protein transferase activity	IDA IDA: Inferred from direct assay	21229326	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to misfolded protein	IMP IMP: Inferred from mutant phenotype	21855799	MGI
involved in proteasome-mediated ubiquitin-dependent protein catabolic process	IMP IMP: Inferred from mutant phenotype	21855799	MGI
involved in protein monoubiquitination	IDA IDA: Inferred from direct assay	21855799	MGI
involved in protein monoubiquitination	IMP IMP: Inferred from mutant phenotype	21229326	MGI
involved in protein quality control for misfolded or incompletely synthesized proteins	IMP IMP: Inferred from mutant phenotype	21855799	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	21229326	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ubiquitin-conjugating enzyme E2 W

E2 ubiquitin-conjugating enzyme W	N-terminal E2 ubiquitin-conjugating enzyme
N-terminus-conjugating E2	probable ubiquitin-conjugating enzyme E2 W
ubiquitin carrier protein W	ubiquitin-protein ligase W

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15366	UBE2W Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20124	Ube2w Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS26628	Ube2w Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ube2w	NCBI	NCBI:55284

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