2. Gene
  3. Sostdc1 - sclerostin domain containing 1 Gene

Sostdc1 - sclerostin domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Wise; Sostl; USAG-1; ectodin; 0610006G05Rik

Gene ID: 66042 | Gene type: protein coding

About Sostdc1

Summary

Predicted to enable BMP binding activity and BMP Receptor activity. Acts upstream of or within several processes, including animal organ development; negative regulation of cell fate commitment; and negative regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human SOSTDC1 (sclerostin domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Sostdc1 Products(1)

mRNA Protein Name
NM_025312.3 NP_079588.1 sclerostin domain-containing protein 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
14623234 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of BMP signaling pathway IDA
IDA: Inferred from direct assay
16179481 MGI
acts upstream of BMP signaling pathway IGI
IGI: Inferred from genetic interaction
16179481 MGI
acts upstream of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of cell fate commitment IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of epithelial cell fate commitment IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of or within hair follicle morphogenesis IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of or within mammary gland bud morphogenesis IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of or within negative regulation of BMP signaling pathway IDA
IDA: Inferred from direct assay
14623234 MGI
acts upstream of or within negative regulation of BMP signaling pathway IGI
IGI: Inferred from genetic interaction
16179481 MGI
acts upstream of or within negative regulation of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of or within negative regulation of cell fate commitment IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IGI
IGI: Inferred from genetic interaction
16179481 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IMP
IMP: Inferred from mutant phenotype
16179481 MGI
acts upstream of or within pattern specification process IMP
IMP: Inferred from mutant phenotype
16179481 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
14623234 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sclerostin domain-containing protein 1

cystine-knot containing secreted protein

ectodermal BMP inhibitor

sclerostin-like protein

uterine sensitization-associated gene 1 protein

uterine sensitization-associated protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13579 SOSTDC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22046 Sostdc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sostdc1 NCBI NCBI:25928