Adamts4 - ADAM metallopeptidase with thrombospondin type 1 motif, 4 Gene

Rattus norvegicus

Gene ID: 66015 | Gene type: protein coding

About Adamts4

Summary

Predicted to enable metalloendopeptidase activity and protease binding activity. Involved in tooth eruption. Predicted to be located in extracellular space and nuclear speck. Predicted to be active in extracellular matrix. Biomarker of degenerative disc disease and transient cerebral ischemia. Orthologous to human ADAMTS4 (ADAM metallopeptidase with thrombospondin type 1 motif 4). [provided by Alliance of Genome Resources, Apr 2022]

Adamts4 Products(1)

mRNA	Protein	Name
NM_023959.1	NP_076449.1	A disintegrin and metalloproteinase with thrombospondin motifs 4

Protein Preferred Names

Protein Names

A disintegrin and metalloproteinase with thrombospondin motifs 4

ADAM-TS 4	ADAM-TS4
ADAMTS-4	Aggrecanase
a disintegrin and metallopeptidase with thrombospondin motifs 4	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
aggrecanase-1

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-137430	Aldumastat	Inhibitor	99.36%	Phase 2

Pre-clinical Phase

Bioactive Molecules (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-101448	TMI-1		99.59%	Unkown
HY-145061	ADAMTS-5-IN-3	Inhibitor	98.89%	Unkown
HY-114996	ADAMTS-5 Inhibitor	Inhibitor	99.30%	Unkown
HY-P10398	5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA		92.55%	Unkown
HY-P5419A	WAAG-3R TFA		99.94%	Unkown
HY-P10468	5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2		/	Unkown
HY-RS00304	ADAMTS4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-160822	AGG-523	Inhibitor	/	Unkown
HY-RS18103	Adamts4 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS24577	Adamts4 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Adamts4	NCBI	NCBI:9507

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