2. Gene
  3. Ifi30 - interferon gamma inducible protein 30 Gene

Ifi30 - interferon gamma inducible protein 30 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as GILT; IP30

Gene ID: 65972 | Gene type: protein coding

About Ifi30

Summary

Predicted to enable oxidoreductase activity, acting on a sulfur group of donors. Involved in antigen processing and presentation of exogenous peptide antigen via MHC class I. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II; negative regulation of fibroblast proliferation; and protein stabilization. Located in lysosome. Is expressed in alimentary system; liver; and orbito-sphenoid. Orthologous to human IFI30 (IFI30 lysosomal thiol reductase). [provided by Alliance of Genome Resources, Apr 2022]

Ifi30 Products(1)

mRNA Protein Name
NM_023065.3 NP_075552.2 gamma-interferon-inducible lysosomal thiol reductase precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in antigen processing and presentation of exogenous peptide antigen via MHC class I IMP
IMP: Inferred from mutant phenotype
20538950 MGI
acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II IMP
IMP: Inferred from mutant phenotype
11701933 MGI
acts upstream of or within negative regulation of fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
18218638 MGI
acts upstream of or within protein stabilization IMP
IMP: Inferred from mutant phenotype
18218638 MGI
Cellular Component GO Annotation Evidence Reference Source
located in lysosome IDA
IDA: Inferred from direct assay
11701933 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-interferon-inducible lysosomal thiol reductase

gamma-interferon-inducible protein IP-30

lysosomal thio reductase IP30

lysosomal thiol reductase IP30

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06554 IFI30 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19445 Ifi30 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25937 Ifi30 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ifi30 NCBI NCBI:10437