2. Gene
  3. Slit1 - slit guidance ligand 1 Gene

Slit1 - slit guidance ligand 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as MEGF4

Gene ID: 65047 | Gene type: protein coding

About Slit1

Summary

Enables heparan sulfate proteoglycan binding activity. Involved in brain development; negative regulation of axon extension involved in axon guidance; and spinal cord development. Located in extracellular space. Orthologous to human SLIT1 (slit guidance ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Slit1 Products(1)

mRNA Protein Name
NM_022953.2 NP_075242.1 slit homolog 1 protein precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables heparan sulfate proteoglycan binding IDA
IDA: Inferred from direct assay
10364234 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15528323 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of axon extension involved in axon guidance IDA
IDA: Inferred from direct assay
15632296 RGD
involved in spinal cord development IEP
IEP: Inferred from expression pattern
10102268 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
15632296 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

slit homolog 1 protein

multiple EGF-like domains protein 4

multiple epidermal growth factor-like domains 4

multiple epidermal growth factor-like domains protein 4

slit-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13370 SLIT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13372 SLIT3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20490 Slit3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21757 Slit1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28275 Slit1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slit1 NCBI NCBI:6585