Map1lc3b - microtubule-associated protein 1 light chain 3 beta Gene

Rattus norvegicus

Also known as LC3B; Mpl3; zbs559; Map1lc3

Gene ID: 64862 | Gene type: protein coding

About Map1lc3b

Summary

Enables microtubule binding activity and protein domain specific binding activity. Involved in positive regulation of protein binding activity. Located in several cellular components, including autophagosome membrane; dendrite; and neuronal cell body. Part of microtubule associated complex. Orthologous to several human genes including MAP1LC3B (microtubule associated protein 1 light chain 3 beta). [provided by Alliance of Genome Resources, Apr 2022]

Map1lc3b Products(1)

mRNA	Protein	Name
NM_022867.2	NP_074058.2	microtubule-associated proteins 1A/1B light chain 3B

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables microtubule binding	IDA IDA: Inferred from direct assay	7908909	RGD
enables protein domain specific binding	IPI IPI: Inferred from physical interaction	7908909	RGD
enables tubulin binding	IDA IDA: Inferred from direct assay	7908909	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in autophagosome membrane	IDA IDA: Inferred from direct assay	15169837	RGD
located in axon	IDA IDA: Inferred from direct assay	7908909	RGD
located in dendrite	IDA IDA: Inferred from direct assay	7908909	RGD
part of microtubule associated complex	IDA IDA: Inferred from direct assay	7908909	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	7908909	RGD
is active in presynapse	IDA IDA: Inferred from direct assay	31784514	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

microtubule-associated proteins 1A/1B light chain 3B

MAP1 light chain 3-like protein 2	MAP1A/1B light chain 3 B
MAP1A/MAP1B LC3 B	MAP1A/MAP1B light chain 3 B
autophagy-related protein LC3 B	autophagy-related ubiquitin-like modifier LC3 B
microtubule-associated proteins 1A/1B light chain 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08029	MAP1LC3B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08030	MAP1LC3B2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS18108	Map1lc3b Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24582	Map1lc3b Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Map1lc3b	NCBI	NCBI:81631

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