MEIG1 - meiosis/spermiogenesis associated 1 Gene

Homo sapiens

Also known as SPATA39; bA2K17.3

Gene ID: 644890 | Gene type: protein coding

About MEIG1

Cytogenetic location: 10p13 Genomic coordinates (GRCh38): 10:14,954,228-14,988,050 (from NCBI)

This gene has 5 transcripts (splice variants) and 175 orthologues. Biased expression in testis (RPKM 4.2) and brain (RPKM 0.2).

Summary

Predicted to act upstream of or within cellular protein localization; manchette assembly; and sperm axoneme assembly. Predicted to be located in cytosol and manchette. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

MEIG1 Products(1)

mRNA	Protein	Name
NM_001080836.3	NP_001074305.1	meiosis expressed gene 1 protein homolog

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MEIG1 Protein Structure

Meiosis_expr

0
88 a.a.

Protein Preferred Names

Protein Names

meiosis expressed gene 1 protein homolog

meiosis expressed gene 1 homolog

MEIG1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	MEIG1	Q5JSS6	PACRG	Homo sapiens	Q96M98-2	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Cardiomyopathy, Familial Hypertrophic, 7

Hypertrophic Cardiomyopathy 7	CMH7
Cardiomyopathy, Familial Hypertrophic 7	Cardiomyopathy, Hypertrophic, 7
Cardiomyopathy, Hypertrophic, Familial, Type 7

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08321	MEIG1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	MEIG1	VGNC	VGNC:31379
Canis familiaris	MEIG1	VGNC	VGNC:43151
Mus musculus	MEIG1	MGD	MGI:1202878
Felis catus	MEIG1	VGNC	VGNC:63447
Rattus norvegicus	MEIG1	RGD	RGD:1583655
Macaca mulatta	MEIG1	VGNC	VGNC:106072

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