2. Gene
  3. Hspd1 - heat shock protein family D (Hsp60) member 1 Gene

Hspd1 - heat shock protein family D (Hsp60) member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hsp60; Hspd1-30p

Gene ID: 63868 | Gene type: protein coding

About Hspd1

Summary

Enables modification-dependent protein binding activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of cytokine production; and response to ischemia. Located in several cellular components, including mitochondrial crista; peroxisomal matrix; and zymogen granule. Used to study Alzheimer's disease and low tension glaucoma. Biomarker of several diseases, including artery disease (multiple); hydrocephalus; hyperglycemia; pulmonary fibrosis; and varicocele. Human ortholog(s) of this gene implicated in artery disease (multiple); autistic disorder; glucose intolerance; hereditary spastic paraplegia (multiple); and hypomyelinating leukodystrophy 4. Orthologous to human HSPD1 (heat shock protein family D (Hsp60) member 1). [provided by Alliance of Genome Resources, Apr 2022]

Hspd1 Products(1)

mRNA Protein Name
NM_022229.2 NP_071565.2 60 kDa heat shock protein, mitochondrial
Protein Preferred Names Protein Names

60 kDa heat shock protein, mitochondrial

60 kDa chaperonin

CPN60

HSP-60

HSP-65

chaperonin 60

heat shock 60kD protein 1 (chaperonin)

heat shock 60kDa protein 1

heat shock protein 1 (chaperonin)

heat shock protein 60 (liver)

heat shock protein family D member 1

mitochondrial matrix prote

Hspd1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Hspd1 P63039 Bax Rattus norvegicus Q63690
Anti Bait CoIP
16579988
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0890 Tubeimoside I 99.96% Unkown
HY-115715 EN219 99.21% Unkown
HY-115715A EN219-alkyne 99.62% Unkown
HY-N0890R Tubeimoside I (Standard) Inducer / Unkown
HY-RS06447 HSPD1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18520 Hspd1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25002 Hspd1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hspd1 NCBI NCBI:3329
Mus musculus Hspd1 NCBI NCBI:15510