2. Gene
  3. Cxcl6 - C-X-C motif chemokine ligand 6 Gene

Cxcl6 - C-X-C motif chemokine ligand 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Cxcl5

Gene ID: 60665 | Gene type: protein coding

About Cxcl6

Summary

Enables chemokine activity. Involved in several processes, including cellular response to lipopolysaccharide; positive regulation of receptor signaling pathway via JAK-STAT; and response to gamma radiation. Located in extracellular space. Used to study colon carcinoma. Biomarker of prostatitis and severe acute respiratory syndrome. Human ortholog(s) of this gene implicated in idiopathic pulmonary fibrosis. Orthologous to several human genes including CXCL6 (C-X-C motif chemokine ligand 6). [provided by Alliance of Genome Resources, Apr 2022]

Cxcl6 Products(1)

mRNA Protein Name
NM_022214.2 NP_071550.2 C-X-C motif chemokine 5 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chemokine activity IMP
IMP: Inferred from mutant phenotype
12468547 RGD
Biological Process GO Annotation Evidence Reference Source
involved in animal organ regeneration IMP
IMP: Inferred from mutant phenotype
9788656 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
15778492 RGD
involved in midbrain development IEP
IEP: Inferred from expression pattern
18436867 RGD
involved in positive regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
21114767 RGD
involved in positive regulation of receptor signaling pathway via JAK-STAT IDA
IDA: Inferred from direct assay
21114767 RGD
involved in response to gamma radiation IEP
IEP: Inferred from expression pattern
20185578 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
15778492 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-X-C motif chemokine 5

CXC chemokine LIX

chemokine (C-X-C motif) ligand 5

chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)

cytokine LIX

small-inducible cytokine B5

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03394 CXCL6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16639 Cxcl5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24115 Cxcl6 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cxcl6 NCBI NCBI:6372