2. Gene
  3. CDKL3 - Cdkl3 cyclin-dependent kinase-like 3 Gene

CDKL3 - Cdkl3 cyclin-dependent kinase-like 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Nkiatre; Nkiatreb

Gene ID: 60396 | Gene type: protein coding

About CDKL3

Summary

Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within dendrite extension; negative regulation of axon extension; and positive regulation of dendrite morphogenesis. Located in cytoplasm and nucleus. Orthologous to human CDKL3 (cyclin dependent kinase like 3). [provided by Alliance of Genome Resources, Apr 2022]

CDKL3 Products(1)

mRNA Protein Name
NM_021772.2 NP_068540.1 cyclin-dependent kinase-like 3
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within dendrite extension IMP
IMP: Inferred from mutant phenotype
20347982 RGD
acts upstream of or within negative regulation of axon extension IMP
IMP: Inferred from mutant phenotype
20347982 RGD
acts upstream of or within positive regulation of dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
20347982 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
20347982 RGD
located in nucleus IDA
IDA: Inferred from direct assay
20347982 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclin-dependent kinase-like 3

serine/threonine kinase NKIATRE beta

serine/threonine protein kinase NKIATRE

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-161847 HZ1 Inhibitor 99.20% Unkown
HY-RS02407 CDKL3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21518 Cdkl3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28036 Cdkl3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CDKL3 NCBI NCBI:51265