2. Gene
  3. Lmna - lamin A/C Gene

Lmna - lamin A/C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 60374 | Gene type: protein coding

About Lmna

Summary

Enables protein Phosphatase 1 binding activity. Involved in several processes, including cellular senescence; negative regulation of adipose tissue development; and positive regulation of osteoblast differentiation. Located in nuclear matrix. Used to study transient cerebral ischemia. Biomarker of arteriosclerosis. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 2B1; intrinsic cardiomyopathy (multiple); lipodystrophy (multiple); muscular dystrophy (multiple); and type 2 diabetes mellitus (multiple). Orthologous to human LMNA (lamin A/C). [provided by Alliance of Genome Resources, Apr 2022]

Lmna Products(1)

mRNA Protein Name
NM_001002016.2 NP_001002016.2 prelamin-A/C
Protein Preferred Names Protein Names

prelamin-A/C

lamin A

lamin C2

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07714 LMNA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-144451 TRK-IN-12 Inhibitor / Unkown
HY-163366 TRK-IN-28 Inhibitor / Unkown
HY-RS19910 Lmna Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26411 Lmna Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lmna NCBI NCBI:4000