2. Gene
  3. Ereg - epiregulin Gene

Ereg - epiregulin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 59325 | Gene type: protein coding

About Ereg

Summary

Enables growth factor activity. Involved in several processes, including female gamete generation; positive regulation of macromolecule metabolic process; and positive regulation of mitotic nuclear division. Located in extracellular space. Human ortholog(s) of this gene implicated in extrapulmonary tuberculosis; pulmonary tuberculosis; and tuberculosis. Orthologous to human EREG (Epiregulin). [provided by Alliance of Genome Resources, Apr 2022]

Ereg Products(1)

mRNA Protein Name
NM_021689.1 NP_067721.1 proepiregulin preproprotein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables growth factor activity IDA
IDA: Inferred from direct assay
9990076 RGD
Biological Process GO Annotation Evidence Reference Source
involved in epidermal growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
9990076 RGD
involved in female meiotic nuclear division IDA
IDA: Inferred from direct assay
15459120 RGD
involved in luteinizing hormone signaling pathway IDA
IDA: Inferred from direct assay
15459120 RGD
involved in oocyte maturation IDA
IDA: Inferred from direct assay
15459120 RGD
involved in ovarian cumulus expansion IDA
IDA: Inferred from direct assay
15459120 RGD
involved in ovulation IDA
IDA: Inferred from direct assay
15459120 RGD
involved in positive regulation of DNA replication IDA
IDA: Inferred from direct assay
9990076 RGD
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
9990076 RGD
involved in positive regulation of mitotic nuclear division IDA
IDA: Inferred from direct assay
9990076 RGD
involved in positive regulation of smooth muscle cell proliferation IDA
IDA: Inferred from direct assay
9990076 RGD
involved in positive regulation of smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
14570897 RGD
involved in primary follicle stage IDA
IDA: Inferred from direct assay
15459120 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
15459120 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
14570897 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proepiregulin

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04487 EREG Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16966 Ereg Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23409 Ereg Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ereg NCBI NCBI:2069
Mus musculus Ereg NCBI NCBI:13874