2. Gene
  3. Kcnk1 - potassium two pore domain channel subfamily K member 1 Gene

Kcnk1 - potassium two pore domain channel subfamily K member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Twik

Gene ID: 59324 | Gene type: protein coding

About Kcnk1

Summary

Enables potassium ion leak channel activity. Involved in potassium ion transmembrane transport and response to nicotine. Located in apical plasma membrane; brush border membrane; and cytoplasm. Is integral component of plasma membrane. Orthologous to human KCNK1 (potassium two pore domain channel subfamily K member 1). [provided by Alliance of Genome Resources, Apr 2022]

Kcnk1 Products(1)

mRNA Protein Name
NM_021688.3 NP_067720.1 potassium channel subfamily K member 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables potassium ion leak channel activity IDA
IDA: Inferred from direct assay
19571146 RGD
Biological Process GO Annotation Evidence Reference Source
involved in potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
19571146 RGD
involved in response to nicotine IEP
IEP: Inferred from expression pattern
11478936 RGD
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
12855359 RGD
located in brush border membrane IDA
IDA: Inferred from direct assay
9843722 RGD
located in plasma membrane IMP
IMP: Inferred from mutant phenotype
19571146 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium channel subfamily K member 1

inward rectifying potassium channel protein TWIK-1

potassium channel K2P1

potassium channel, subfamily K, member 1

potassium channel, two pore domain subfamily K, member 1

putative potassium channel TWIK

rTWIK

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07152 KCNK1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21612 Kcnk1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28130 Kcnk1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnk1 NCBI NCBI:3775