2. Gene
  3. Ptges - prostaglandin E synthase Gene

Ptges - prostaglandin E synthase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pges; mPGES-1

Gene ID: 59103 | Gene type: protein coding

About Ptges

Summary

Enables prostaglandin-D synthase activity and prostaglandin-E synthase activity. Involved in several processes, including prostaglandin biosynthetic process; response to lipopolysaccharide; and response to retinoic acid. Located in intracellular membrane-bounded organelle and perinuclear region of cytoplasm. Biomarker of Barrett's esophagus; ischemia; papilloma; peptic esophagitis; and transitional cell carcinoma. Orthologous to human PTGES (prostaglandin E synthase). [provided by Alliance of Genome Resources, Apr 2022]

Ptges Products(1)

mRNA Protein Name
NM_021583.3 NP_067594.1 prostaglandin E synthase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables prostaglandin-D synthase activity IDA
IDA: Inferred from direct assay
10869354 RGD
enables prostaglandin-E synthase activity IDA
IDA: Inferred from direct assay
11067848 RGD
Biological Process GO Annotation Evidence Reference Source
involved in chronic inflammatory response IEP
IEP: Inferred from expression pattern
12707354 RGD
involved in prostaglandin biosynthetic process IDA
IDA: Inferred from direct assay
11067848 RGD
involved in response to calcium ion IEP
IEP: Inferred from expression pattern
16598755 RGD
involved in response to cytokine IEP
IEP: Inferred from expression pattern
16816110 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
18383341 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
17927823 RGD
involved in response to retinoic acid IEP
IEP: Inferred from expression pattern
18183617 RGD
Cellular Component GO Annotation Evidence Reference Source
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
15284079 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prostaglandin E synthase

glutathione peroxidase PTGES

glutathione transferase PTGES

inducible prostaglandin E synthase

microsomal prostaglandin E synthase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11379 PTGES Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11380 PTGES2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11381 PTGES3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19734 Ptges Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19804 Ptges2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19805 Ptges3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26230 Ptges Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26300 Ptges2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26301 Ptges3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptges NCBI NCBI:9536