Degs1 - delta(4)-desaturase, sphingolipid 1 Gene

Rattus norvegicus

Also known as Degs

Gene ID: 58970 | Gene type: protein coding

About Degs1

Summary

Predicted to enable retinol isomerase activity and sphingolipid delta-4 desaturase activity. Predicted to be involved in ceramide biosynthetic process and myelin maintenance. Predicted to act upstream of or within positive regulation of apoptotic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human DEGS1 (delta 4-desaturase, sphingolipid 1). [provided by Alliance of Genome Resources, Apr 2022]

Degs1 Products(1)

mRNA	Protein	Name
NM_053323.2	NP_445775.2	sphingolipid delta(4)-desaturase DES1

Protein Preferred Names

Protein Names

sphingolipid delta(4)-desaturase DES1

degenerative spermatocyte homolog 1, lipid desaturase	degenerative spermatocyte-like protein RDES
dihydroceramide desaturase-1	retinol isomerase

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-153665	Deg-1		99.45%	Unkown
HY-RS03682	DEGS1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21551	Degs1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS28069	Degs1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Degs1	NCBI	NCBI:8560

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