2. Gene
  3. Nr1h2 - nuclear receptor subfamily 1, group H, member 2 Gene

Nr1h2 - nuclear receptor subfamily 1, group H, member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as LXRB; OR-1; LXRbeta; LXR beta

Gene ID: 58851 | Gene type: protein coding

About Nr1h2

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and retinoid X receptor binding activity. Contributes to sequence-specific DNA binding activity. Involved in regulation of gene expression; response to nutrient levels; and retinoic acid receptor signaling pathway. Predicted to be located in cytoplasm and nucleus. Biomarker of obesity. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human NR1H2 (nuclear receptor subfamily 1 group H member 2). [provided by Alliance of Genome Resources, Apr 2022]

Nr1h2 Products(4)

mRNA Protein Name
NM_001398609.1 NP_001385538.1 oxysterols receptor LXR-beta isoform a
NM_001398610.1 NP_001385539.1 oxysterols receptor LXR-beta isoform a
NM_001398611.1 NP_001385540.1 oxysterols receptor LXR-beta isoform b
NM_031626.3 NP_113814.2 oxysterols receptor LXR-beta isoform b
Protein Preferred Names Protein Names

oxysterols receptor LXR-beta

UR

liver X receptor beta

nuclear orphan receptor LXR-beta

orphan nuclear receptor OR-1

ubiquitous receptor

ubiquitously-expressed nuclear receptor

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09529 NR1H2 Human Pre-designed siRNA Set A / Unkown
HY-RS19726 Nr1h2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26222 Nr1h2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nr1h2 NCBI NCBI:7376