Cdon - cell adhesion molecule-related/down-regulated by oncogenes Gene

Mus musculus

Also known as CDO; Cd0; Orcam

Gene ID: 57810 | Gene type: protein coding

About Cdon

Summary

Acts upstream of or within several processes, including animal organ development; positive regulation of intracellular signal transduction; and positive regulation of nitrogen compound metabolic process. Predicted to be located in cell surface. Predicted to be integral component of plasma membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; limb bud; and sensory organ. Used to study holoprosencephaly 11. Human ortholog(s) of this gene implicated in holoprosencephaly 11. Orthologous to human CDON (cell adhesion associated, oncogene regulated). [provided by Alliance of Genome Resources, Apr 2022]

Cdon Products(7)

mRNA	Protein	Name
NM_001405246.1	NP_001392175.1	cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_001405247.1	NP_001392176.1	cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_001405248.1	NP_001392177.1	cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_001405249.1	NP_001392178.1	cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_001405250.1	NP_001392179.1	cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_001405251.1	NP_001392180.1	cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_021339.3	NP_067314.2	cell adhesion molecule-related/down-regulated by oncogenes precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11782431	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within anterior/posterior pattern specification	IMP IMP: Inferred from mutant phenotype	19754878	MGI
acts upstream of or within cell fate specification	IGI IGI: Inferred from genetic interaction	16647304	MGI
acts upstream of or within cerebral cortex development	IMP IMP: Inferred from mutant phenotype	16648472	MGI
acts upstream of or within embryonic body morphogenesis	IGI IGI: Inferred from genetic interaction	16647304	MGI
acts upstream of or within embryonic body morphogenesis	IMP IMP: Inferred from mutant phenotype	16647303	MGI
acts upstream of or within embryonic morphogenesis	IGI IGI: Inferred from genetic interaction	17504941	MGI
acts upstream of or within embryonic retina morphogenesis in camera-type eye	IMP IMP: Inferred from mutant phenotype	19754878	MGI
acts upstream of or within lens development in camera-type eye	IMP IMP: Inferred from mutant phenotype	19754878	MGI
acts upstream of or within myoblast fusion	IMP IMP: Inferred from mutant phenotype	15520228	MGI
acts upstream of neural precursor cell proliferation	IMP IMP: Inferred from mutant phenotype	16648472	MGI
acts upstream of neuroblast proliferation	IMP IMP: Inferred from mutant phenotype	16648472	MGI
acts upstream of neuron differentiation	IMP IMP: Inferred from mutant phenotype	19244314	MGI
acts upstream of or within positive regulation of MAPK cascade	IGI IGI: Inferred from genetic interaction	20160094	MGI
acts upstream of or within positive regulation of MAPK cascade	IMP IMP: Inferred from mutant phenotype	19244314	MGI
acts upstream of or within positive regulation of neuroblast proliferation	IMP IMP: Inferred from mutant phenotype	16648472	MGI
acts upstream of or within positive regulation of neuron differentiation	IDA IDA: Inferred from direct assay	16648472	MGI
acts upstream of or within positive regulation of neuron differentiation	IMP IMP: Inferred from mutant phenotype	16648472	MGI
acts upstream of or within positive regulation of protein phosphorylation	IDA IDA: Inferred from direct assay	15572127	MGI
acts upstream of or within positive regulation of skeletal muscle tissue development	IMP IMP: Inferred from mutant phenotype	15572127	MGI
acts upstream of or within positive regulation of small GTPase mediated signal transduction	IMP IMP: Inferred from mutant phenotype	19244314	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IGI IGI: Inferred from genetic interaction	15572127	MGI
acts upstream of protein phosphorylation	IDA IDA: Inferred from direct assay	15572127	MGI
acts upstream of or within regulation of neuron differentiation	IMP IMP: Inferred from mutant phenotype	16648472	MGI
acts upstream of or within regulation of protein binding	IDA IDA: Inferred from direct assay	15572127	MGI
acts upstream of or within skeletal muscle satellite cell differentiation	IMP IMP: Inferred from mutant phenotype	15572127	MGI
acts upstream of skeletal muscle tissue development	IMP IMP: Inferred from mutant phenotype	15572127	MGI
acts upstream of or within smoothened signaling pathway	IGI IGI: Inferred from genetic interaction	16647304	MGI
acts upstream of or within striated muscle cell differentiation	IGI IGI: Inferred from genetic interaction	20160094	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cell adhesion molecule-related/down-regulated by oncogenes

CAM-related/down-regulated by oncogenes	immunoglobulin superfamily member CDO
oncogene-regulated cell adhesion molecule

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02422	CDON Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS19882	Cdon Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS26381	Cdon Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cdon	NCBI	NCBI:50937

Name
Email *

	Sorry, but the email address you supplied was invalid.