2. Gene
  3. Ehd3 - EH-domain containing 3 Gene

Ehd3 - EH-domain containing 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ehd2

Gene ID: 57440 | Gene type: protein coding

About Ehd3

Summary

Predicted to enable calcium ion binding activity; lipid binding activity; and purine ribonucleoside triphosphate binding activity. Involved in cilium assembly; positive regulation of voltage-gated Calcium Channel activity; and regulation of heart contraction. Acts upstream of or within protein localization to plasma membrane and regulation of cardiac muscle cell membrane potential. Located in endocytic vesicle and perinuclear region of cytoplasm. Is expressed in several structures, including adrenal gland; central nervous system; ganglia; otic capsule; and turbinate bone primordium. Orthologous to human EHD3 (EH domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Ehd3 Products(1)

mRNA Protein Name
NM_020578.3 NP_065603.2 EH domain-containing protein 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12121420 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
25686250 MGI
involved in positive regulation of voltage-gated calcium channel activity IMP
IMP: Inferred from mutant phenotype
25825486 MGI
acts upstream of or within protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
20489164 MGI
involved in regulation of cardiac conduction IMP
IMP: Inferred from mutant phenotype
25825486 MGI
acts upstream of or within regulation of cardiac muscle cell membrane potential IMP
IMP: Inferred from mutant phenotype
20489164 MGI
involved in regulation of cardiac muscle contraction IMP
IMP: Inferred from mutant phenotype
25825486 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17251388 MGI
located in endocytic vesicle IDA
IDA: Inferred from direct assay
12121420 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
20489164 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

EH domain-containing protein 3

EH-domain containing protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS28674 Ehd3 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ehd3 NCBI NCBI:30845