1. Gene
  2. Cldn9 - claudin 9 Gene

Cldn9 - claudin 9 Gene

Mus musculus

Also known as nmf329

Gene ID: 56863 | Gene type: protein coding

About Cldn9

Summary

This intronless gene encodes a member of the Claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is developmentally regulated; it is expressed in neonate kidney, but disappers by adulthood. It is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness. [provided by RefSeq, Aug 2010]

Cldn9 Products(1)

mRNA Protein Name
NM_020293.3 NP_064689.2 claudin-9
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cell-cell junction organization IDA
IDA: Inferred from direct assay
17130295 MGI
acts upstream of or within tight junction organization IDA
IDA: Inferred from direct assay
17130295 MGI
Cellular Component GO Annotation Evidence Reference Source
located in bicellular tight junction IDA
IDA: Inferred from direct assay
17130295 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
17130295 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

claudin-9

Orthologs Information

Species Symbol Source ID
Homo sapiens Cldn9 NCBI NCBI:9080