2. Gene
  3. Srgn - serglycin Gene

Srgn - serglycin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pgsg

Gene ID: 56782 | Gene type: protein coding

About Srgn

Summary

Enables Collagen binding activity. Predicted to be involved in several processes, including granzyme-mediated programmed cell death signaling pathway; negative regulation of bone mineralization; and protein localization to secretory granule. Located in zymogen granule. Colocalizes with Golgi membrane. Orthologous to human SRGN (serglycin). [provided by Alliance of Genome Resources, Apr 2022]

Srgn Products(1)

mRNA Protein Name
NM_020074.3 NP_064459.1 serglycin precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables collagen binding IDA
IDA: Inferred from direct assay
9207929 RGD
Cellular Component GO Annotation Evidence Reference Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
12602945 RGD
located in zymogen granule IDA
IDA: Inferred from direct assay
12602945 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serglycin

PG19 core protein

chondroitin sulfate proteoglycan core protein

cytolytic granule proteoglycan core protein

proteoglycan 10K core protein

proteoglycan peptide core protein

secretory granule proteoglycan core protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13766 SRGN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17592 Srgn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24052 Srgn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srgn NCBI NCBI:5552