2. Gene
  3. Klk4 - kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) Gene

Klk4 - kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PSTS; ESMP1; KLK-L1; Prss17

Gene ID: 56640 | Gene type: protein coding

About Klk4

Summary

Predicted to enable metal ion binding activity and serine-type endopeptidase activity. Acts upstream of or within amelogenesis; extracellular matrix disassembly; and protein catabolic process. Predicted to be located in extracellular region. Predicted to be active in secretory granule. Is expressed in epididymis; ileum; prostate gland; skin; and upper jaw incisor. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 2A1 and prostate Cancer. Orthologous to human KLK4 (Kallikrein related peptidase 4). [provided by Alliance of Genome Resources, Apr 2022]

Klk4 Products(1)

mRNA Protein Name
NM_019928.2 NP_064312.1 kallikrein-4 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within amelogenesis IMP
IMP: Inferred from mutant phenotype
19578120 MGI
acts upstream of or within extracellular matrix disassembly IMP
IMP: Inferred from mutant phenotype
22243248 MGI
acts upstream of or within protein catabolic process IMP
IMP: Inferred from mutant phenotype
22243248 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kallikrein-4

enamel matrix serine proteinase 1

kallikrein-like protein 1

protease, serine 17 (enamel matrix, prostate)

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07382 KLK4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20292 Klk4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26800 Klk4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klk4 NCBI NCBI:9622