B4galt5 - UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 Gene

Mus musculus

Also known as 9430078I07Rik

Gene ID: 56336 | Gene type: protein coding

About B4galt5

Summary

Enables N-acetyllactosamine synthase activity and UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity. Involved in several processes, including ganglioside biosynthetic process via lactosylceramide; neurogenesis; and positive regulation of embryonic development. Acts upstream of or within poly-N-acetyllactosamine biosynthetic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including epithelium; genitourinary system; heart; nervous system; and respiratory system. Orthologous to human B4GALT5 (beta-1,4-galactosyltransferase 5). [provided by Alliance of Genome Resources, Apr 2022]

B4galt5 Products(1)

mRNA	Protein	Name
NM_019835.2	NP_062809.2	beta-1,4-galactosyltransferase 5

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables N-acetyllactosamine synthase activity	IMP IMP: Inferred from mutant phenotype	20417617	MGI
enables UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	IMP IMP: Inferred from mutant phenotype	20574042	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in central nervous system myelination	IMP IMP: Inferred from mutant phenotype	30114188	MGI
involved in central nervous system neuron axonogenesis	IMP IMP: Inferred from mutant phenotype	30114188	MGI
involved in ganglioside biosynthetic process via lactosylceramide	IMP IMP: Inferred from mutant phenotype	30114188	MGI
involved in neuron maturation	IMP IMP: Inferred from mutant phenotype	30114188	MGI
acts upstream of or within poly-N-acetyllactosamine biosynthetic process	IMP IMP: Inferred from mutant phenotype	20417617	MGI
involved in positive regulation of embryonic development	IMP IMP: Inferred from mutant phenotype	20574042	MGI
involved in protein glycosylation	IMP IMP: Inferred from mutant phenotype	29415997	MGI
involved in regulation of protein stability	IMP IMP: Inferred from mutant phenotype	29415997	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

beta-1,4-galactosyltransferase 5

UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5	UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5
b4Gal-T5	beta-1,4-GalT II
beta-1,4-GalTase 5	beta-1,4-galactosyltransferase V
beta4Gal-T5	glucosylceramide beta-1,4-galacto

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-114364	UDP-Galactose disodium	Agonist	99.42%	Unkown
HY-RS01323	B4GALT5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19086	B4galt5 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25576	B4galt5 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	B4galt5	NCBI	NCBI:9334

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