2. Gene
  3. Higd1a - HIG1 domain family, member 1A Gene

Higd1a - HIG1 domain family, member 1A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hig1; HIMP1; 2210020B17Rik; 7420700H20Rik

Gene ID: 56295 | Gene type: protein coding

About Higd1a

Summary

Acts upstream of or within several processes, including cellular response to glucose starvation; negative regulation of release of cytochrome c from mitochondria; and positive regulation of protein serine/threonine kinase activity. Located in mitochondrial inner membrane and nucleus. Orthologous to human HIGD1A (HIG1 hypoxia inducible domain family member 1A). [provided by Alliance of Genome Resources, Apr 2022]

Higd1a Products(6)

mRNA Protein Name
NM_001357837.1 NP_001344766.1 HIG1 domain family member 1A, mitochondrial
NM_001357838.1 NP_001344767.1 HIG1 domain family member 1A, mitochondrial
NM_001357839.1 NP_001344768.1 HIG1 domain family member 1A, mitochondrial
NM_001357840.1 NP_001344769.1 HIG1 domain family member 1A, mitochondrial
NM_001357841.1 NP_001344770.1 HIG1 domain family member 1A, mitochondrial
NM_019814.5 NP_062788.1 HIG1 domain family member 1A, mitochondrial
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to glucose starvation IDA
IDA: Inferred from direct assay
16815968 MGI
acts upstream of or within cellular response to glucose starvation IMP
IMP: Inferred from mutant phenotype
25683712 MGI
acts upstream of or within cellular response to hypoxia IDA
IDA: Inferred from direct assay
16815968 MGI
acts upstream of or within cellular response to hypoxia IMP
IMP: Inferred from mutant phenotype
25683712 MGI
acts upstream of or within negative regulation of release of cytochrome c from mitochondria IDA
IDA: Inferred from direct assay
21856340 MGI
acts upstream of or within positive regulation of protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
25683712 MGI
Cellular Component GO Annotation Evidence Reference Source
located in membrane IDA
IDA: Inferred from direct assay
16815968 MGI
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
16815968 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
21856340 MGI
located in nucleus IDA
IDA: Inferred from direct assay
23646141 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

HIG1 domain family member 1A, mitochondrial

hypoxia induced gene 1

hypoxia-inducible gene 1 protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06171 HIGD1A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21864 Higd1a Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Higd1a NCBI NCBI:25994