2. Gene
  3. Plek - pleckstrin Gene

Plek - pleckstrin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2010300B13Rik

Gene ID: 56193 | Gene type: protein coding

About Plek

Summary

Predicted to enable phosphatidylinositol-3,4-bisphosphate binding activity; protein homodimerization activity; and protein kinase C binding activity. Involved in several processes, including exocytosis; platelet aggregation; and positive regulation of cellular component organization. Predicted to be located in cytoplasm and ruffle membrane. Predicted to be active in plasma membrane. Orthologous to human PLEK (pleckstrin). [provided by Alliance of Genome Resources, Apr 2022]

Plek Products(1)

mRNA Protein Name
NM_019549.2 NP_062422.1 pleckstrin
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in platelet aggregation IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in positive regulation of actin filament depolymerization IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in positive regulation of integrin activation IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in positive regulation of platelet activation IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in protein secretion by platelet IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in thrombin-activated receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in vesicle docking involved in exocytosis IMP
IMP: Inferred from mutant phenotype
19190246 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pleckstrin

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10677 PLEK Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10678 PLEK2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19367 Plek Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22732 Plek2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25859 Plek Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plek NCBI NCBI:5341