Elovl2 - elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 Gene

Mus musculus

Also known as Ssc2

Gene ID: 54326 | Gene type: protein coding

About Elovl2

Summary

Enables fatty acid elongase activity. Involved in fatty acid elongation, polyunsaturated fatty acid and very long-chain fatty acid biosynthetic process. Acts upstream of or within very long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including brain; liver; paravertebral ganglion; sensory organ; and urinary system. Orthologous to human ELOVL2 (ELOVL fatty acid elongase 2). [provided by Alliance of Genome Resources, Apr 2022]

Elovl2 Products(2)

mRNA	Protein	Name
NM_001311121.1	NP_001298050.1	elongation of very long chain fatty acids protein 2 isoform 2
NM_019423.2	NP_062296.1	elongation of very long chain fatty acids protein 2 isoform 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables acyltransferase activity, transferring groups other than amino-acyl groups	IDA IDA: Inferred from direct assay	11567032	MGI
enables fatty acid elongase activity	IDA IDA: Inferred from direct assay	12371743	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in fatty acid elongation, polyunsaturated fatty acid	IDA IDA: Inferred from direct assay	12371743	MGI
involved in fatty acid elongation, polyunsaturated fatty acid	IMP IMP: Inferred from mutant phenotype	21106902	MGI
involved in very long-chain fatty acid biosynthetic process	IDA IDA: Inferred from direct assay	12371743	MGI
involved in very long-chain fatty acid biosynthetic process	IMP IMP: Inferred from mutant phenotype	21106902	MGI
acts upstream of or within very long-chain fatty acid metabolic process	IDA IDA: Inferred from direct assay	11567032	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

elongation of very long chain fatty acids protein 2

3-keto acyl-CoA synthase Elovl2	ELOVL FA elongase 2
ELOVL family member 2	ELOVL fatty acid elongase 2
sequence similarity to Cig30 2	very long chain 3-ketoacyl-CoA synthase 2
very long chain 3-oxoacyl-CoA synthase 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04322	ELOVL2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21122	Elovl2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27641	Elovl2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Elovl2	NCBI	NCBI:54898

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