2. Gene
  3. Slk - STE20-like kinase Gene

Slk - STE20-like kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as SK2; Stk2

Gene ID: 54308 | Gene type: protein coding

About Slk

Summary

Enables protein kinase activity. Involved in several processes, including cellular response to tumor necrosis factor; positive regulation of histone phosphorylation; and protein autophosphorylation. Located in cytoplasm. Orthologous to human SLK (STE20 like kinase). [provided by Alliance of Genome Resources, Apr 2022]

Slk Products(1)

mRNA Protein Name
NM_019349.2 NP_062222.2 STE20-like serine/threonine-protein kinase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables histone kinase activity IDA
IDA: Inferred from direct assay
21572393 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
18420945 RGD
enables protein kinase activity IDA
IDA: Inferred from direct assay
18420945 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to tumor necrosis factor IEP
IEP: Inferred from expression pattern
21572393 RGD
involved in cellular response to type II interferon IDA
IDA: Inferred from direct assay
21572393 RGD
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
21572393 RGD
involved in protein autophosphorylation IDA
IDA: Inferred from direct assay
12965890 RGD
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
12965890 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

STE20-like serine/threonine-protein kinase

STE20-related kinase

STE20-related serine/threonine-protein kinase

serine/threonine kinase 2

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-111553 TAS0728 Inhibitor 99.71% Phase 1
Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-132868 SLK/STK10-IN-1 Inhibitor 99.78% Unkown
HY-103647 K00546 Inhibitor 98.08% Unkown
HY-150782 UNC-CA359 Inhibitor / Unkown
HY-RS05174 FYN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13379 SLK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17069 Slk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23513 Slk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slk NCBI NCBI:9748