2. Gene
  3. Nasp - nuclear autoantigenic sperm protein (histone-binding) Gene

Nasp - nuclear autoantigenic sperm protein (histone-binding) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Epcs32; Nasp-T; D4Ertd767e; 5033430J04Rik

Gene ID: 50927 | Gene type: protein coding

About Nasp

Summary

Enables histone binding activity. Involved in G1/S transition of mitotic cell cycle; blastocyst development; and histone exchange. Acts upstream of or within DNA replication-dependent chromatin assembly. Located in cytoplasm and nucleus. Is expressed in several structures, including brain ventricular layer; extraembryonic component; lung; metanephros; and rest of cerebellum marginal layer. Orthologous to human NASP (nuclear autoantigenic sperm protein). [provided by Alliance of Genome Resources, Apr 2022]

Nasp Products(3)

mRNA Protein Name
NM_001081475.1 NP_001074944.1 nuclear autoantigenic sperm protein isoform 1
NM_001284229.1 NP_001271158.1 nuclear autoantigenic sperm protein isoform 3
NM_016777.3 NP_058057.3 nuclear autoantigenic sperm protein isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables histone binding IDA
IDA: Inferred from direct assay
10893414 MGI
enables histone chaperone activity IDA
IDA: Inferred from direct assay
12509435 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10893414 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within DNA replication-dependent chromatin assembly IDA
IDA: Inferred from direct assay
16728391 MGI
involved in DNA replication-dependent chromatin assembly IDA
IDA: Inferred from direct assay
12509435 MGI
involved in G1/S transition of mitotic cell cycle IDA
IDA: Inferred from direct assay
16728391 MGI
involved in blastocyst development IMP
IMP: Inferred from mutant phenotype
16728391 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12509435 MGI
located in nucleus IDA
IDA: Inferred from direct assay
10893414 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear autoantigenic sperm protein

somatic histone binding protein NASP

Nasp Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Nasp Q99MD9 H1-2 Mus musculus P15864
Anti Bait CoIP
10893414
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-176305S Neurofilament, U-15N / Unkown
HY-RS09038 NASP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20303 Nasp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26811 Nasp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nasp NCBI NCBI:4678