2. Gene
  3. Pnpla6 - patatin-like phospholipase domain containing 6 Gene

Pnpla6 - patatin-like phospholipase domain containing 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Nte; MSws

Gene ID: 50767 | Gene type: protein coding

About Pnpla6

Summary

Enables lysophospholipase activity. Acts upstream of or within angiogenesis and animal organ morphogenesis. Located in membrane. Is expressed in several structures, including brain; cranial nerve; epithelium; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in Boucher-Neuhauser syndrome; Laurence-Moon syndrome; Oliver-McFarlane syndrome; and hereditary spastic paraplegia 39. Orthologous to human PNPLA6 (patatin like Phospholipase domain containing 6). [provided by Alliance of Genome Resources, Apr 2022]

Pnpla6 Products(11)

mRNA Protein Name
NM_001122818.3 NP_001116290.2 patatin-like phospholipase domain-containing protein 6 isoform 1
NM_001359121.2 NP_001346050.1 patatin-like phospholipase domain-containing protein 6 isoform 3
NM_001359122.2 NP_001346051.1 patatin-like phospholipase domain-containing protein 6 isoform 4
NM_001359123.2 NP_001346052.1 patatin-like phospholipase domain-containing protein 6 isoform 5
NM_001359124.2 NP_001346053.1 patatin-like phospholipase domain-containing protein 6 isoform 6
NM_001378951.1 NP_001365880.1 patatin-like phospholipase domain-containing protein 6 isoform 1
NM_001378952.1 NP_001365881.1 patatin-like phospholipase domain-containing protein 6 isoform 3
NM_001378953.1 NP_001365882.1 patatin-like phospholipase domain-containing protein 6 isoform 7
NM_001378954.1 NP_001365883.1 patatin-like phospholipase domain-containing protein 6 isoform 8
NM_001378955.1 NP_001365884.1 patatin-like phospholipase domain-containing protein 6 isoform 9
NM_015801.3 NP_056616.2 patatin-like phospholipase domain-containing protein 6 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables lysophospholipase activity IDA
IDA: Inferred from direct assay
18086666 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within angiogenesis IMP
IMP: Inferred from mutant phenotype
14749382 MGI
acts upstream of or within animal organ morphogenesis IMP
IMP: Inferred from mutant phenotype
14749382 MGI
Cellular Component GO Annotation Evidence Reference Source
located in membrane IDA
IDA: Inferred from direct assay
18086666 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

patatin-like phospholipase domain-containing protein 6

Swiss-cheese

neuropathy target esterase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10797 PNPLA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20581 Pnpla6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27089 Pnpla6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pnpla6 NCBI NCBI:10908