2. Gene
  3. Dkkl1 - dickkopf-like 1 Gene

Dkkl1 - dickkopf-like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SGY; SGY1; mSgy; SGY-1; Soggy

Gene ID: 50722 | Gene type: protein coding

About Dkkl1

Summary

Predicted to enable co-receptor binding activity and receptor antagonist activity. Involved in negative regulation of testosterone biosynthetic process; penetration of zona pellucida; and positive regulation of apoptotic process. Acts upstream of or within positive regulation of fat cell differentiation. Located in acrosomal vesicle. Is expressed in several structures, including extraembryonic component and reproductive system. Orthologous to human DKKL1 (dickkopf like acrosomal protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Dkkl1 Products(1)

mRNA Protein Name
NM_015789.3 NP_056604.2 dickkopf-like protein 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19176879 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within canonical Wnt signaling pathway IDA
IDA: Inferred from direct assay
29715368 MGI
involved in negative regulation of testosterone biosynthetic process IMP
IMP: Inferred from mutant phenotype
18818293 MGI
involved in penetration of zona pellucida IMP
IMP: Inferred from mutant phenotype
19596312 MGI
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
18818293 MGI
acts upstream of or within positive regulation of fat cell differentiation IDA
IDA: Inferred from direct assay
12055200 MGI
Cellular Component GO Annotation Evidence Reference Source
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
15892050 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dickkopf-like protein 1

protein soggy-1

soggy 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03791 DKKL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20011 Dkkl1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26514 Dkkl1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dkkl1 NCBI NCBI:27120