Sftpc - surfactant protein C Gene

Rattus norvegicus

Also known as SP-C

Gene ID: 50683 | Gene type: protein coding

About Sftpc

Summary

Enables identical protein binding activity. Involved in several processes, including cellular response to mechanical stimulus; cellular response to nitric oxide; and response to vitamin A. Located in alveolar lamellar body; extracellular space; and multivesicular body. Biomarker of Bacterial pneumonia and newborn respiratory distress syndrome. Human ortholog(s) of this gene implicated in asthma; lung disease (multiple); and respiratory syncytial virus infectious disease. Orthologous to human SFTPC (surfactant protein C). [provided by Alliance of Genome Resources, Apr 2022]

Sftpc Products(1)

mRNA	Protein	Name
NM_017342.2	NP_059038.1	pulmonary surfactant-associated protein C

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	11907042	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to mechanical stimulus	IEP IEP: Inferred from expression pattern	12600831	RGD
involved in cellular response to nitric oxide	IEP IEP: Inferred from expression pattern	15640287	RGD
involved in circadian rhythm	IEP IEP: Inferred from expression pattern	12872443	RGD
involved in response to cAMP	IEP IEP: Inferred from expression pattern	1319687	RGD
involved in response to glucocorticoid	IEP IEP: Inferred from expression pattern	1319687	RGD
involved in response to glucose	IEP IEP: Inferred from expression pattern	10027080	RGD
involved in response to growth factor	IEP IEP: Inferred from expression pattern	11076805	RGD
involved in response to hormone	IEP IEP: Inferred from expression pattern	9779374	RGD
involved in response to hyperoxia	IEP IEP: Inferred from expression pattern	11472975	RGD
involved in response to interleukin-6	IEP IEP: Inferred from expression pattern	11000512	RGD
involved in response to lipopolysaccharide	IEP IEP: Inferred from expression pattern	11000512	RGD
involved in response to retinoic acid	IEP IEP: Inferred from expression pattern	9505268	RGD
involved in response to vitamin A	IEP IEP: Inferred from expression pattern	10385596	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in alveolar lamellar body	IDA IDA: Inferred from direct assay	2001226	RGD
located in extracellular space	IDA IDA: Inferred from direct assay	11704537	RGD
located in multivesicular body	IDA IDA: Inferred from direct assay	16187065	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

pulmonary surfactant-associated protein C

Surfactant, pulmonary-associated protein C	pulmonary surfactant-associated proteolipid SPL(Val)
surfactant associated protein C

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12783	SFTPC Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21754	Sftpc Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS28272	Sftpc Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sftpc	NCBI	NCBI:6440

Name
Email *

	Sorry, but the email address you supplied was invalid.