2. Gene
  3. Acot1 - acyl-CoA thioesterase 1 Gene

Acot1 - acyl-CoA thioesterase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Cte1

Gene ID: 50559 | Gene type: protein coding

About Acot1

Summary

Enables acyl-CoA hydrolase activity. Involved in long-chain fatty acid metabolic process and negative regulation of cardiac muscle cell apoptotic process. Located in cytosol. Orthologous to several human genes including ACOT1 (acyl-CoA thioesterase 1). [provided by Alliance of Genome Resources, Apr 2022]

Acot1 Products(1)

mRNA Protein Name
NM_031315.2 NP_112605.1 acyl-coenzyme A thioesterase 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables fatty acyl-CoA hydrolase activity IDA
IDA: Inferred from direct assay
7906114 RGD
Biological Process GO Annotation Evidence Reference Source
involved in long-chain fatty acid metabolic process IDA
IDA: Inferred from direct assay
7906114 RGD
involved in negative regulation of cardiac muscle cell apoptotic process IMP
IMP: Inferred from mutant phenotype
23226270 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acyl-coenzyme A thioesterase 1

ACH2

CTE-I

LACH2

acyl-CoA thioesterase 1, cytosolic

cytosolic acyl-CoA thioesterase 1

inducible cytosolic acyl-coenzyme A thioester hydrolase

long chain acyl-CoA hydrolase

long chain acyl-CoA thioester hydrolase

palmitoyl-coenzyme A thioesterase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00173 ACOT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21470 Acot1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27988 Acot1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acot1 NCBI NCBI:641371