2. Gene
  3. Aplf - aprataxin and PNKP like factor Gene

Aplf - aprataxin and PNKP like factor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1565557

Gene ID: 500247 | Gene type: protein coding

About Aplf

Summary

Predicted to enable DNA-(apurinic or apyrimidinic site) Endonuclease activity; nuclease activity; and nucleotide binding activity. Predicted to be involved in double-strand break repair via nonhomologous end joining and single strand break repair. Predicted to act upstream of or within positive regulation of DNA ligation and regulation of isotype switching. Predicted to be located in nucleoplasm. Predicted to be active in nucleus and site of double-strand break. Orthologous to human APLF (aprataxin and PNKP like factor). [provided by Alliance of Genome Resources, Apr 2022]

Aplf Products(1)

mRNA Protein Name
NM_001173382.1 NP_001166853.1 aprataxin and PNK-like factor
Protein Preferred Names Protein Names

aprataxin and PNK-like factor

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00821 APLF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22105 Aplf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28626 Aplf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aplf NCBI NCBI:200558