2. Gene
  3. En2 - engrailed homeobox 2 Gene

En2 - engrailed homeobox 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1561842

Gene ID: 499964 | Gene type: protein coding

About En2

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including embryonic brain development; negative regulation of neuron apoptotic process; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within nervous system development and positive regulation of transcription by RNA polymerase II. Located in membrane and nucleus. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human EN2 (engrailed homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

En2 Products(1)

mRNA Protein Name
NM_001109214.1 NP_001102684.1 homeobox protein engrailed-2
Protein Preferred Names Protein Names

homeobox protein engrailed-2

engrailed 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-34748 3-Penten-2-one / Unkown
HY-RS04366 EN2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-402815 (E)-4-(Naphthalen-2-yl)but-3-en-2-one / Unkown
HY-N1024 11R,12-Dihydroxyspirovetiv-1(10)-en-2-one / Unkown
HY-N1024A 11S,12-Dihydroxyspirovetiv-1(10)-en-2-one / Unkown
HY-N1759 3,11,12-Trihydroxyspirovetiv-1(10)-en-2-one / Unkown
HY-N9018 4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one / Unkown
HY-RS18020 En2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24493 En2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens En2 NCBI NCBI:2020
Macaca fascicularis En2 NCBI NCBI:102116747
Mus musculus En2 NCBI NCBI:13799