2. Gene
  3. Purb - purine rich element binding protein B Gene

Purb - purine rich element binding protein B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as pur-beta

Gene ID: 498407 | Gene type: protein coding

About Purb

Summary

Enables purine-rich negative regulatory element binding activity; single-stranded DNA binding activity; and translation repressor activity, mRNA regulatory element binding. Involved in negative regulation of transcription, DNA-templated. Located in nucleus. Orthologous to human PURB (purine rich element binding protein B). [provided by Alliance of Genome Resources, Apr 2022]

Purb Products(1)

mRNA Protein Name
NM_001017503.2 NP_001017503.2 transcriptional activator protein Pur-beta
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12933792 RGD
enables mRNA regulatory element binding translation repressor activity IDA
IDA: Inferred from direct assay
12933792 RGD
enables purine-rich negative regulatory element binding IDA
IDA: Inferred from direct assay
12933792 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12933792 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in nucleus IDA
IDA: Inferred from direct assay
12933792 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcriptional activator protein Pur-beta

transcription factor Pur-beta

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11465 PURB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21412 Purb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27931 Purb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Purb NCBI NCBI:5814