DBX2 - developing brain homeobox 2 Gene

Homo sapiens

Gene ID: 440097 | Gene type: protein coding

About DBX2

This gene has 1 transcript (splice variant), 187 orthologues and 3 paralogues. Biased expression in brain (RPKM 1.7), testis (RPKM 0.5) and 2 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

DBX2 Products(1)

mRNA	Protein	Name
NM_001004329.3	NP_001004329.2	homeobox protein DBX2

DBX2 Protein Structure

Homeobox

0
100
200
300
339 a.a.

Protein Preferred Names

Protein Names

homeobox protein DBX2

developing brain homeobox protein 2

Related Diseases

Diseases

Alias

Miles-Carpenter Syndrome

X-Linked Intellectual Disability, Miles-Carpenter Type	Mcs
Mental Retardation, X-Linked, Syndromic 4	Mental Retardation, X-Linked, With Congenital Contractures And Low Fingertip Arches
Mrxs4	Miles-Carpenter X-Linked Mental Retardation Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03556	DBX2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	DBX2	MGD	MGI:107445
Macaca mulatta	DBX2	VGNC	VGNC:108334
Bos taurus	DBX2	VGNC	VGNC:27898
Rattus norvegicus	DBX2	RGD	RGD:1359605
Canis familiaris	DBX2	VGNC	VGNC:57422

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