2. Gene
  3. Fut8 - fucosyltransferase 8 Gene

Fut8 - fucosyltransferase 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 432392 | Gene type: protein coding

About Fut8

Summary

Predicted to enable glycoprotein 6-alpha-L-fucosyltransferase activity. Predicted to be involved in GDP-L-fucose metabolic process; N-glycan fucosylation; and protein N-linked glycosylation via asparagine. Predicted to act upstream of or within several processes, including N-glycan processing; cell surface receptor signaling pathway; and regulation of cellular response to oxidative stress. Predicted to be located in Golgi cisterna membrane. Predicted to be integral component of membrane. Orthologous to human FUT8 (fucosyltransferase 8). [provided by Alliance of Genome Resources, Apr 2022]

Fut8 Products(2)

mRNA Protein Name
NM_001002289.2 NP_001002289.2 alpha-(1,6)-fucosyltransferase
NM_001412189.1 NP_001399118.1 alpha-(1,6)-fucosyltransferase
Protein Preferred Names Protein Names

alpha-(1,6)-fucosyltransferase

GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase

GDP-fucose--glycoprotein fucosyltransferase

alpha1-6FucT

fucosyltransferase 8 (alpha (1,6) fucosyltransferase)

glycoprotein 6-alpha-L-fucosyltransferase

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-155747 FDW028 Inhibitor 99.51% Unkown
HY-E70157 Fucosyltransferase 8 / Unkown
HY-170541 FUT8-IN-1 Inhibitor / Unkown
HY-RS05159 FUT8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17190 Fut8 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23641 Fut8 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99010A Bemarituzumab (FUT8-KO) Inhibitor 99.74% Unkown
HY-P99113A Inebilizumab (FUT8-KO) 97% Unkown
HY-P9980A Belantamab (FUT-8 KO) 98.10% Unkown
HY-P99406A Petosemtamab (FUT8-KO) / Unkown
HY-P99653A Ianalumab (FUT8-KO) Inhibitor / Unkown
HY-P9991A Osemitamab (FUT8-KO) / Unkown
HY-P9977A Amivantamab (FUT8-KO) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fut8 NCBI NCBI:2530