Trim56 - tripartite motif-containing 56 Gene

Mus musculus

Also known as Gm452; RNF109; A130009K11Rik

Gene ID: 384309 | Gene type: protein coding

About Trim56

Summary

Enables ubiquitin protein Ligase activity. Involved in several processes, including defense response to Other organism; positive regulation of interferon-beta production; and protein K63-linked ubiquitination. Located in cytoplasm. Orthologous to human TRIM56 (tripartite motif containing 56). [provided by Alliance of Genome Resources, Apr 2022]

Trim56 Products(1)

mRNA	Protein	Name
NM_201373.4	NP_958761.1	E3 ubiquitin-protein ligase TRIM56

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21074459	MGI
enables ubiquitin protein ligase activity	IDA IDA: Inferred from direct assay	21074459	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in defense response to virus	IDA IDA: Inferred from direct assay	29426904	MGI
involved in defense response to virus	IMP IMP: Inferred from mutant phenotype	21074459	MGI
involved in innate immune response	IDA IDA: Inferred from direct assay	18248090	MGI
involved in negative regulation of viral entry into host cell	IDA IDA: Inferred from direct assay	18248090	MGI
involved in positive regulation of interferon-beta production	IMP IMP: Inferred from mutant phenotype	21074459	MGI
involved in positive regulation of type I interferon-mediated signaling pathway	IDA IDA: Inferred from direct assay	29426904	MGI
involved in protein K63-linked ubiquitination	IDA IDA: Inferred from direct assay	21074459	MGI
involved in protein monoubiquitination	IDA IDA: Inferred from direct assay	29426904	MGI
involved in response to type I interferon	IDA IDA: Inferred from direct assay	21074459	MGI
involved in suppression of viral release by host	IDA IDA: Inferred from direct assay	18248090	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	21074459	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

E3 ubiquitin-protein ligase TRIM56

RING-type E3 ubiquitin transferase TRIM56

tripartite motif-containing protein 56

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15057	TRIM56 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21963	Trim56 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Trim56	NCBI	NCBI:81844

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