2. Gene
  3. Best3 - bestrophin 3 Gene

Best3 - bestrophin 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Vmd2l3; mBest4

Gene ID: 382427 | Gene type: protein coding

About Best3

Summary

Enables Chloride Channel activity. Acts upstream of or within inorganic anion transport and negative regulation of ion transport. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of Chloride Channel complex. Orthologous to human BEST3 (bestrophin 3). [provided by Alliance of Genome Resources, Apr 2022]

Best3 Products(1)

mRNA Protein Name
NM_001007583.1 NP_001007584.1 bestrophin-3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chloride channel activity IDA
IDA: Inferred from direct assay
16563389 MGI
NOT enables ligand-gated monoatomic anion channel activity IMP
IMP: Inferred from mutant phenotype
18414923 MGI
enables ligand-gated monoatomic anion channel activity IMP
IMP: Inferred from mutant phenotype
18414923 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within inorganic anion transport IDA
IDA: Inferred from direct assay
16563389 MGI
acts upstream of or within negative regulation of monoatomic ion transport IDA
IDA: Inferred from direct assay
16563389 MGI
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
18414923 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bestrophin-3

vitelliform macular dystrophy 2-like 3

vitelliform macular dystrophy 2-like protein 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01476 BEST3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21498 Best3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Best3 NCBI NCBI:144453